Compound Detail
CHEMBL523952
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Basic Information
| ChEMBL ID | CHEMBL523952 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BDDBEOZZUSMPQL-HMUNZLOLSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
313.3
MW (Da)
-0.76
ALogP
8
HBA
4
HBD
111.7
PSA (Ų)
0.57
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 4.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form CHEMBL4696 | Ki | 4.58 | 4.58 | 26000.0 | 2 |
| Unchecked CHEMBL612545 | Ki | 4.58 | 4.58 | 26000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form | Ki | = | 26000.0 | nM | 4.58 | Inhibition of rabbit muscle glycogen phosphorylase b | 18793852 |
| Glycogen phosphorylase, muscle form | Ki | = | 26000.0 | nM | 4.58 | Inhibition of rabbit muscle glycogen phosphorylase b by Dixon plot analysis | 19574053 |
| Unchecked | Ki | = | 26000.0 | nM | 4.58 | Inhibition of rabbit muscle Glycogen phosphorylase b using alpha-D-glucose-1-pho... | 31251604 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18793852 | 10.1016/j.bmcl.2008.08.052 | Glycogen phosphorylase, muscle form | 1 |
| 19574053 | 10.1016/j.bmc.2009.05.080 | Glycogen phosphorylase, muscle form | 1 |
| 31251604 | 10.1021/acs.jmedchem.9b00356 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine