Compound Detail
CHEMBL526127
POCHONIN D Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL526127 |
| Name | POCHONIN D |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FJVQHTGEXYKKBS-CJRGTMQESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
350.8
MW (Da)
3.70
ALogP
5
HBA
2
HBD
83.8
PSA (Ų)
0.55
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Heat shock protein HSP 90-beta CHEMBL4303 | IC50 | 7.1 | 7.1 | 80.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Heat shock protein HSP 90-beta | IC50 | = | 80.0 | nM | 7.1 | Inhibition of Hsp90 | 19017562 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12828470 | 10.1021/np020556v | Human alphaherpesvirus 1 | 1 |
| 12828470 | 10.1021/np020556v | Vero | 1 |
| 12828470 | 10.1021/np020556v | Neospora caninum | 1 |
| 12828470 | 10.1021/np020556v | Estrogen receptor beta | 1 |
| 12828470 | 10.1021/np020556v | ADMET | 1 |
| 12828470 | 10.1021/np020556v | Eimeria tenella | 1 |
| 19017562 | 10.1016/j.bmc.2008.10.087 | Heat shock protein HSP 90-beta | 1 |
Data from ChEMBL 36 via Core Engine