Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL526286

PIPERKADSIN A
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
C=CCC1=C[C@@](OC)(/C(C)=C/c2ccc(O)c(OC)c2)C(OC)=CC1=O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL526286
Name PIPERKADSIN A
Phase Preclinical
Structure Type MOL
InChI Key JSWLJDNWLQCBNE-PAGBRTJLSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

356.4
MW (Da)
3.80
ALogP
5
HBA
1
HBD
65.0
PSA (Ų)
0.75
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C21H24O5
MW 356.42
Aromatic Rings 1
Heavy Atoms 26
NP-Likeness 2.15

Activity Summary

IC50 1 meas. best 5.37

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
 IC50 5.37 5.37 4300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET IC50 = 4300.0 nM 5.37 Antiinflammatory activity in human PMN assessed as inhibition of Phorbol-12-myri... 16724856

Literature References

PubMed DOI Target Context # Activities
16724856 10.1021/np0505521 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine