Compound Detail
CHEMBL5284333
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Basic Information
| ChEMBL ID | CHEMBL5284333 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AJVOTIYZWULLBY-HNNXBMFYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
347.5
MW (Da)
4.25
ALogP
4
HBA
2
HBD
71.5
PSA (Ų)
0.67
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.59
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 4.59 | 4.59 | 25800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 25800.0 | nM | 4.59 | Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells preincubated ... | 36746775 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36746775 | 10.1021/acs.jnatprod.2c00861 | RAW264.7 | 3 |
| 36746775 | 10.1021/acs.jnatprod.2c00861 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine