Compound Detail
CHEMBL5285142
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Basic Information
| ChEMBL ID | CHEMBL5285142 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VMCCMDQEUZHYOI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
228.3
MW (Da)
0.87
ALogP
5
HBA
1
HBD
72.3
PSA (Ų)
0.72
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Catenin beta-1/Transcription factor 7 CHEMBL3885542 | IC50 | 5.5 | 5.5 | 3140.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Catenin beta-1/Transcription factor 7 | IC50 | = | 3140.0 | nM | 5.5 | Inhibition of human beta-catenin (142 to 686 residues)/human TCF (7 to 51 residu... | 33445154 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33445154 | 10.1016/j.ejmech.2020.113149 | Catenin beta-1/Transcription factor 7 | 1 |
Data from ChEMBL 36 via Core Engine