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Target Snapshot

CHEMBL3885542 Target Snapshot

Catenin beta-1/Transcription factor 7 · PROTEIN-PROTEIN INTERACTION · Homo sapiens

9Compounds
7Assays
0Approved Drugs
8.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P36402. Use UniProt P36402 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P36402 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Catenin beta-1/Transcription factor 7 as ChEMBL target CHEMBL3885542, mapped to UniProt P36402. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Catenin beta-1/Transcription factor 7
PROTEIN-PROTEIN INTERACTION · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3885542
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P36402
Transcription factor 7
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Catenin beta-1/Transcription factor 7 is the right protein anchor across sources, using UniProt P36402 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTranscription factor 7
UniProt AccessionP36402
Component TypeProtein
Sequence Length384 aa

Transcription factor 7

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Catenin beta-1/Transcription factor 7, mapped to UniProt P36402. ChEMBL maps the protein component as Transcription factor 7. Sequence length is 384 aa.

Mapped IDP36402
Review nameCatenin beta-1/Transcription factor 7
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

IC506.0
KI2.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5189409 6.36 Ki 440.0 Preclinical
CHEMBL4451478 6.19 Ki 640.0 Preclinical
CHEMBL2312139 5.52 IC50 3000.0 Preclinical
CHEMBL5291202 5.52 IC50 3000.0 Preclinical
CHEMBL5285142 5.5 IC50 3140.0 Preclinical
CHEMBL5268653 5.26 IC50 5440.0 Preclinical
CHEMBL1097925 5.22 IC50 6000.0 Preclinical
CHEMBL5273461 5.0 IC50 10000.0 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
3
5.5
2
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
8
Tested Compounds
1
Assay Types
Binding — 7 assays, 8 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 4 5.4
protein format 3 4 5.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine