Compound Detail
CHEMBL5289271
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Basic Information
| ChEMBL ID | CHEMBL5289271 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HMMWQKKXVBVONG-ZRDIBKRKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
364.5
MW (Da)
6.45
ALogP
4
HBA
0
HBD
15.6
PSA (Ų)
0.52
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 8.77 | 8.77 | 1.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 1.7 | nM | 8.77 | Antiinflammatory activity in carrageenan induced rat paw edema model assessed in... | 32795767 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32795767 | 10.1016/j.ejmech.2020.112666 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine