Compound Detail
CHEMBL538288
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL538288 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HJLCDHHCMDDUPE-IPZCTEOASA-N |
| Parent Compound | CHEMBL1189224 |
| Active Moiety | CHEMBL1189224 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
409.4
MW (Da)
2.18
ALogP
8
HBA
1
HBD
107.0
PSA (Ų)
0.64
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 9.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | Kd | 9.85 | 9.85 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | Kd | = | 0.1413 | nM | 9.85 | Compound was tested for alpha-adrenoceptor blocking activity by its ability to a... | 6131135 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6131135 | 10.1021/jm00357a016 | Rattus norvegicus | 26 |
| 6131135 | 10.1021/jm00357a016 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine