Compound Detail
CHEMBL5394644
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Basic Information
| ChEMBL ID | CHEMBL5394644 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KGBCOMFCBMSVJV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
298.3
MW (Da)
2.45
ALogP
6
HBA
1
HBD
73.6
PSA (Ų)
0.80
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier family 22 member 12 CHEMBL6120 | IC50 | 5.31 | 5.31 | 4850.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 12 | IC50 | = | 4850.0 | nM | 5.31 | Inhibition of human URAT1 stably overexpressing in human HEK293 cells assessed a... | 36001935 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36001935 | 10.1016/j.ejmech.2022.114682 | Solute carrier family 22 member 12 | 1 |
Data from ChEMBL 36 via Core Engine