Compound Detail
CHEMBL5404799
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Basic Information
| ChEMBL ID | CHEMBL5404799 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ADTBZOLAEWCHRQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
372.5
MW (Da)
4.53
ALogP
4
HBA
2
HBD
65.0
PSA (Ų)
0.52
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Epidermal growth factor receptor CHEMBL203 | IC50 | 8.35 | 8.35 | 4.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | IC50 | = | 4.5 | nM | 8.35 | Inhibition of EGFR (unknown origin) | 37191268 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37191268 | 10.1021/acs.jmedchem.3c00428 | Macrophage colony-stimulating factor 1 receptor | 1 |
| 37191268 | 10.1021/acs.jmedchem.3c00428 | Epidermal growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine