Compound Detail
CHEMBL5421242
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Basic Information
| ChEMBL ID | CHEMBL5421242 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AEKXFKTYWDQZGU-GOSISDBHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
364.9
MW (Da)
4.60
ALogP
3
HBA
2
HBD
37.2
PSA (Ų)
0.52
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dynamin-1 CHEMBL4958 | IC50 | 4.76 | 4.76 | 17500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dynamin-1 | IC50 | = | 17500.0 | nM | 4.76 | Inhibition of phosphotidylserine liposome-stimulated Dynamin 1 (unknown origin) ... | 36577213 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36577213 | 10.1016/j.ejmech.2022.115001 | Dynamin-1 | 1 |
Data from ChEMBL 36 via Core Engine