Compound Detail
CHEMBL5422499
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5422499 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NYJHYCNQSAJXIQ-QAPCUYQASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
3.35
ALogP
4
HBA
2
HBD
61.8
PSA (Ų)
0.81
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mu-type opioid receptor CHEMBL233 | EC50 | 7.21 | 7.21 | 62.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mu-type opioid receptor | EC50 | = | 62.0 | nM | 7.21 | Agonist activity at human mu opioid receptor stably transfected in CHO cells by ... | 37414346 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37414346 | 10.1016/j.bmcl.2023.129405 | Mu-type opioid receptor | 2 |
Data from ChEMBL 36 via Core Engine