Compound Detail
CHEMBL5428607
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5428607 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AZCWGVWPUYKTBY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
359.4
MW (Da)
3.76
ALogP
6
HBA
3
HBD
97.4
PSA (Ų)
0.46
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dual specificity protein kinase TTK CHEMBL3983 | IC50 | 7.27 | 7.27 | 54.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dual specificity protein kinase TTK | IC50 | = | 54.0 | nM | 7.27 | Inhibition of Mps1 (unknown origin) incubated for 120 mins in presence of substr... | 36370549 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36370549 | 10.1016/j.ejmech.2022.114887 | Dual specificity protein kinase TTK | 1 |
Data from ChEMBL 36 via Core Engine