Compound Detail
CHEMBL5438210
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CC[C@H](C)[C@H]1C(=O)N[C@@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccc(OC)cc2)C(=O)N(C)[C@H](C)/C=C/[C@H](C)[C@H](N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(=O)N(C)[C@@H](C)C(=O)N1C
Basic Information
| ChEMBL ID | CHEMBL5438210 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NLLURLYURZLKHG-ZVOQMXLTSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
1209.6
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| U-87 MG CHEMBL614247 | IC50 | 7.89 | 7.89 | 13.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| U-87 MG | IC50 | = | 13.0 | nM | 7.89 | Antiproliferative activity against human U-87 MG cells expressing GLuc assessed ... | 37849553 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37849553 | 10.1021/acsmedchemlett.3c00232 | U-87 MG | 5 |
| 37849553 | 10.1021/acsmedchemlett.3c00232 | A549 | 1 |
| 37849553 | 10.1021/acsmedchemlett.3c00232 | HCT-116 | 1 |
| 37849553 | 10.1021/acsmedchemlett.3c00232 | NHDF | 1 |
Data from ChEMBL 36 via Core Engine