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Compound Detail

CHEMBL549473

DIPYRITHIONE
🧪 Phase II
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🧪 Phase II
[O-][n+]1ccccc1SSc1cccc[n+]1[O-]

Basic Information

ChEMBL ID CHEMBL549473
Name DIPYRITHIONE
Phase Phase II
Structure Type MOL
InChI Key ZHDBTKPXEJDTTQ-UHFFFAOYSA-N

Known Names

Bispyrithione Dipiritiona Dipyrithione NSC-241716 NSC-84740 Omadine disulfide OMDS Pyrithione disulfide Pyrithione disulphide
1
Targets
6
Activities
1
Assay Types
0
PK Parameters
4
Publications
9
Known Names

Molecular Properties

252.3
MW (Da)
1.75
ALogP
4
HBA
0
HBD
53.9
PSA (Ų)
0.47
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral

Flags

Natural Product
USAN Year 1972

Extended Properties

Molecular Formula C10H8N2O2S2
MW 252.32
Aromatic Rings 2
Heavy Atoms 16
NP-Likeness -0.03

Activity Summary

IC50 6 meas. best 6.88

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 6.88 6.0817 130.6 6

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
19093848 10.1021/np800572r Staphylococcus aureus 3
19093848 10.1021/np800572r Mycolicibacterium smegmatis 2
19093848 10.1021/np800572r Mycolicibacterium fortuitum 1
19093848 10.1021/np800572r Mycolicibacterium phlei 1

Data from ChEMBL 36 via Core Engine