Compound Detail
CHEMBL5517779
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Basic Information
| ChEMBL ID | CHEMBL5517779 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PQKUSNASLKWMDE-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
175.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.23
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lactoperoxidase CHEMBL5898 | IC50 | 6.23 | 6.23 | 590.0 | 1 |
| No relevant target CHEMBL2362975 | IC50 | 4.91 | 4.91 | 12200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lactoperoxidase | IC50 | = | 590.0 | nM | 6.23 | Inhibition of LPO (unknown origin)-mediated L-tyrosine nitration incubated for 2... | 38716896 |
| No relevant target | IC50 | = | 12200.0 | nM | 4.91 | Antioxidant activity assessed as inhibition of peroxynitrite mediated L-tyrosine... | 38716896 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38716896 | 10.1021/acs.jmedchem.3c02426 | No relevant target | 2 |
| 38716896 | 10.1021/acs.jmedchem.3c02426 | Lactoperoxidase | 2 |
Data from ChEMBL 36 via Core Engine