Compound Detail
CHEMBL55316
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Basic Information
| ChEMBL ID | CHEMBL55316 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DGZPDTKVILQCJY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
320.4
MW (Da)
3.93
ALogP
2
HBA
2
HBD
62.0
PSA (Ų)
0.41
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.93
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Translocator protein CHEMBL4552 | Ki | 5.93 | 5.93 | 1167.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Translocator protein | Ki | = | 1167.0 | nM | 5.93 | Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radio... | 15027878 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15027878 | 10.1021/jm030973k | Translocator protein | 1 |
| 15027878 | 10.1021/jm030973k | GABA-A receptor; anion channel | 1 |
Data from ChEMBL 36 via Core Engine