Compound Detail
CHEMBL5531959
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5531959 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WJLIPCZIYAMTOV-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
340.4
MW (Da)
0.90
ALogP
6
HBA
1
HBD
86.1
PSA (Ų)
0.84
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sclerostin CHEMBL3580487 | Kd | 6.4 | 6.37 | 397.1 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sclerostin | Kd | = | 397.1 | nM | 6.4 | Binding affinity to SOST (unknown origin) by SPR analysis | 38677061 |
| Sclerostin | Kd | = | 453.6 | nM | 6.34 | Binding affinity to SOST loop2 (unknown origin) by SPR analysis | 38677061 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38677061 | 10.1016/j.ejmech.2024.116414 | Sclerostin | 3 |
Data from ChEMBL 36 via Core Engine