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Compound Detail

CHEMBL5549764

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NCCCC[C@@H](N)C(=O)N[C@@H](C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(N)=O)C(c1ccccc1)c1ccccc1

Basic Information

ChEMBL ID CHEMBL5549764
Phase Preclinical
Structure Type MOL
InChI Key JTQHKGRJMXLUMH-WCRWLLLKSA-N
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

1439.8
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C78H106N18O9
MW 1439.82

Activity Summary

IC50 4 meas. best 4.49

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
U-937
CHEMBL612794
IC50 4.49 4.49 32500.0 1
A20
CHEMBL613850
IC50 4.09 4.09 80500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine