Compound Detail
CHEMBL5559214
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5559214 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KYIRGXJWECWXIO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
358.4
MW (Da)
2.56
ALogP
4
HBA
1
HBD
50.8
PSA (Ų)
0.86
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Programmed cell death 1 ligand 1 CHEMBL3580522 | IC50 | 6.21 | 6.21 | 623.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Programmed cell death 1 ligand 1 | IC50 | = | 623.0 | nM | 6.21 | Inhibition of exosomal PD-L1 (unknown origin) generation preincubated with compo... | 38367489 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38367489 | 10.1016/j.ejmech.2024.116182 | Programmed cell death 1 ligand 1 | 1 |
Data from ChEMBL 36 via Core Engine