Compound Detail
CHEMBL5561172
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Basic Information
| ChEMBL ID | CHEMBL5561172 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IBHNEKVLDKCEQY-JVVVGQRLSA-N |
| Parent Compound | CHEMBL481806 |
| Active Moiety | CHEMBL481806 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
441.5
MW (Da)
3.51
ALogP
6
HBA
2
HBD
83.7
PSA (Ų)
0.61
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | IC50 | 8.22 | 8.22 | 6.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor | IC50 | = | 6.0 | nM | 8.22 | Inhibition of CSF1R (unknown origin) | 38330850 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38330850 | 10.1016/j.bmc.2024.117628 | Macrophage colony-stimulating factor 1 receptor | 1 |
Data from ChEMBL 36 via Core Engine