Compound Detail
CHEMBL5565638
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Basic Information
| ChEMBL ID | CHEMBL5565638 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IOVAPCNPVOYVSG-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
353.8
MW (Da)
5.46
ALogP
3
HBA
2
HBD
58.6
PSA (Ų)
0.64
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty acid-binding protein, heart CHEMBL3344 | Ki | 8.66 | 8.66 | 2.2 | 1 |
| Fatty acid-binding protein, adipocyte CHEMBL2083 | Ki | 6.45 | 6.45 | 359.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty acid-binding protein, heart | Ki | = | 2.19 | nM | 8.66 | Displacement of 1,8-ANS from N-terminal 6His-tagged full length FABP3 (unknown o... | 38043490 |
| Fatty acid-binding protein, adipocyte | Ki | = | 359.0 | nM | 6.45 | Displacement of 1,8-ANS from N-terminal 6His-tagged full length FABP4 (unknown o... | 38043490 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38043490 | 10.1016/j.ejmech.2023.115984 | Fatty acid-binding protein, adipocyte | 1 |
| 38043490 | 10.1016/j.ejmech.2023.115984 | Fatty acid-binding protein, heart | 1 |
| 38043490 | 10.1016/j.ejmech.2023.115984 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine