Compound Detail
CHEMBL5572751
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Basic Information
| ChEMBL ID | CHEMBL5572751 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FPXDXLYXLTZJNJ-QGZVFWFLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
326.4
MW (Da)
4.11
ALogP
5
HBA
1
HBD
68.9
PSA (Ų)
0.69
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| BV-2 CHEMBL614781 | IC50 | 4.54 | 4.54 | 29200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| BV-2 | IC50 | = | 29200.0 | nM | 4.54 | Anti-inflammatory activity in mouse BV-2 cells assessed as reduction in LPS-indu... | 37683361 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37683361 | 10.1016/j.ejmech.2023.115791 | BV-2 | 1 |
Data from ChEMBL 36 via Core Engine