Compound Detail

CHEMBL5590171

Enter ChEMBL ID:

Free Research Context This compound will appear in recent viewed items on the research home for this browser.

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL5590171
Phase	Preclinical
Structure Type	MOL
InChI Key	DYUYBVFIJLMSMS-UBZAWCBLSA-N

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Molecular Properties

3879.6

MW (Da)

Drug Information

Availability	Unknown
Chirality	Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula	C171H297N61O42
MW	3879.64

Activity Summary

IC50 1 meas. best 5.16

Target Activity Profile

Target	Type	Best pChEMBL	Mean pChEMBL	Best (nM)	# Data
Erythrocyte CHEMBL4296518	IC50	5.16	5.16	6900.0	1

Activity Data Samples

Top measurements by pChEMBL value

Target	Type	Rel.	Value	Units	pChEMBL	Assay	PubMed
Erythrocyte	IC50	=	6900.0	nM	5.16	Hemolytic activity against human RBC incubated for 1 hr by microplate reader ana...	39116273

Literature References

PubMed	DOI	Target Context	# Activities
39116273	10.1021/acs.jmedchem.4c00912	Lipid bilayer	1
39116273	10.1021/acs.jmedchem.4c00912	Escherichia coli	1
39116273	10.1021/acs.jmedchem.4c00912	Staphylococcus carnosus	1
39116273	10.1021/acs.jmedchem.4c00912	Erythrocyte	1

Data from ChEMBL 36 via Core Engine