Compound Detail
CHEMBL5592585
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Basic Information
| ChEMBL ID | CHEMBL5592585 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OKFIHTSZDXUGQB-PGPNUJALSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
311.3
MW (Da)
1.12
ALogP
4
HBA
4
HBD
123.9
PSA (Ų)
0.39
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hippocampus CHEMBL613631 | EC50 | 5.43 | 5.43 | 3712.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hippocampus | EC50 | = | 3712.0 | nM | 5.43 | Reduction in CA1 spike amplitude in Wistar rat hippocampal slices after 20 mins ... | 39133077 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39133077 | 10.1021/acs.jmedchem.4c01311 | Hippocampus | 1 |
Data from ChEMBL 36 via Core Engine