Compound Detail
CHEMBL560020
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL560020 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QXVFEIPAZSXRGM-DJJJIMSYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
353.4
MW (Da)
4.02
ALogP
3
HBA
2
HBD
75.6
PSA (Ų)
0.82
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.89 | 4.89 | 12800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 12800.0 | nM | 4.89 | Antiinflammatory activity in fMLP/cytochalasin B-stimulated human neutrophils as... | 19110343 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19110343 | 10.1016/j.ejmech.2008.11.008 | NON-PROTEIN TARGET | 2 |
| 30301675 | 10.1016/j.bmcl.2018.09.034 | Chaperone SurA | 1 |
| 32608236 | 10.1021/acs.jmedchem.9b02119 | Sialin | 1 |
| 35450365 | 10.1021/acsmedchemlett.1c00721 | SW480 | 1 |
| 35450365 | 10.1021/acsmedchemlett.1c00721 | HCT-116 | 1 |
| 35450365 | 10.1021/acsmedchemlett.1c00721 | CCD-841CoN | 1 |
Data from ChEMBL 36 via Core Engine