Compound Detail
CHEMBL5618105
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Basic Information
| ChEMBL ID | CHEMBL5618105 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DJUMLBLXPJQEGW-QHHAFSJGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
314.4
MW (Da)
3.64
ALogP
4
HBA
1
HBD
63.6
PSA (Ų)
0.88
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.45
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier family 22 member 12 CHEMBL6120 | IC50 | 5.45 | 5.45 | 3590.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 12 | IC50 | = | 3590.0 | nM | 5.45 | Inhibition of human URAT1 transfected in HEK293 cells by measuring 14C-uric acid... | 39142150 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39142150 | 10.1016/j.ejmech.2024.116753 | Solute carrier family 22 member 12 | 1 |
Data from ChEMBL 36 via Core Engine