Compound Detail
CHEMBL56183
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Basic Information
| ChEMBL ID | CHEMBL56183 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LGRLJXCJYMYBLM-GDBMZVCRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
245.4
MW (Da)
3.30
ALogP
2
HBA
1
HBD
23.5
PSA (Ų)
0.86
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A CHEMBL214 | Ki | 8.41 | 8.41 | 3.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Ki | = | 3.87 | nM | 8.41 | Binding affinity against 5-hydroxytryptamine 1A receptor | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3761309 | 10.1021/jm00160a017 | Dopamine receptor | 2 |
| 3761309 | 10.1021/jm00160a017 | Rattus norvegicus | 2 |
| - | 10.1016/S0960-894X(97)00074-7 | 5-hydroxytryptamine receptor 1A | 1 |
Data from ChEMBL 36 via Core Engine