Compound Detail
CHEMBL5618313
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Basic Information
| ChEMBL ID | CHEMBL5618313 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QPCYWYOFTWPCDP-WUXMJOGZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
394.4
MW (Da)
4.89
ALogP
5
HBA
2
HBD
83.8
PSA (Ų)
0.62
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier family 22 member 12 CHEMBL6120 | IC50 | 6.64 | 6.64 | 230.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 12 | IC50 | = | 230.0 | nM | 6.64 | Inhibition of human URAT1 transfected in HEK293 cells by measuring 14C-uric acid... | 39142150 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39142150 | 10.1016/j.ejmech.2024.116753 | Mus musculus | 6 |
| 39142150 | 10.1016/j.ejmech.2024.116753 | ADMET | 3 |
| 39142150 | 10.1016/j.ejmech.2024.116753 | HK-2 | 2 |
| 39142150 | 10.1016/j.ejmech.2024.116753 | Solute carrier family 22 member 12 | 1 |
| 39142150 | 10.1016/j.ejmech.2024.116753 | Solute carrier family 2, facilitated glucose transporter member 9 | 1 |
Data from ChEMBL 36 via Core Engine