Compound Detail
CHEMBL5618811
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5618811 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HIUCOKHOHORBHA-ONNFQVAWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
437.3
MW (Da)
5.49
ALogP
3
HBA
1
HBD
63.6
PSA (Ų)
0.55
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier family 22 member 12 CHEMBL6120 | IC50 | 6.14 | 6.14 | 730.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 12 | IC50 | = | 730.0 | nM | 6.14 | Inhibition of human URAT1 transfected in HEK293 cells by measuring 14C-uric acid... | 39142150 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39142150 | 10.1016/j.ejmech.2024.116753 | Solute carrier family 22 member 12 | 1 |
Data from ChEMBL 36 via Core Engine