Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL57367

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CCCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21

Basic Information

ChEMBL ID CHEMBL57367
Phase Preclinical
Structure Type MOL
InChI Key SUFMHSFGODDLKI-NHCUHLMSSA-N
2
Targets
6
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names

Molecular Properties

384.6
MW (Da)
7.55
ALogP
2
HBA
0
HBD
18.5
PSA (Ų)
0.36
QED
1
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H40O2
MW 384.60
Aromatic Rings 1
Heavy Atoms 28
NP-Likeness 1.52

Activity Summary

Ki 6 meas. best 8.19

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cannabinoid receptor 2
CHEMBL253
Ki 8.19 7.8633 6.4 3
Cannabinoid receptor 1
CHEMBL218
Ki 5.98 5.1933 1043.0 3

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
- 10.1016/0960-894X(95)00573-C Cannabinoid receptor 2 1
- 10.1016/0960-894X(95)00573-C Cannabinoid receptor 1 1
- 10.1016/0960-894X(95)00573-C Cannabinoid receptor 1
21183257 10.1016/j.ejmech.2010.11.034 Cannabinoid receptor 1 1
21183257 10.1016/j.ejmech.2010.11.034 Cannabinoid receptor 2 1
21183257 10.1016/j.ejmech.2010.11.034 Unchecked 1
23865723 10.1021/jm4005626 Cannabinoid receptor 2 1
23865723 10.1021/jm4005626 Unchecked 1
23865723 10.1021/jm4005626 Cannabinoid receptor 1 1

Data from ChEMBL 36 via Core Engine