Compound Detail
CHEMBL5742220
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Basic Information
| ChEMBL ID | CHEMBL5742220 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DKRLWUXKYKBTLR-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
448.9
MW (Da)
4.75
ALogP
4
HBA
0
HBD
40.9
PSA (Ų)
0.45
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium channel subfamily K member 9 CHEMBL2321614 | IC50 | 7.01 | 7.01 | 98.0 | 1 |
| Potassium channel subfamily K member 3 CHEMBL2321613 | IC50 | 6.46 | 6.46 | 350.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium channel subfamily K member 9 | IC50 | = | 98.0 | nM | 7.01 | Inhibition In Vito Assay: The investigations on the inhibition of the recombinan... | - |
| Potassium channel subfamily K member 3 | IC50 | = | 350.0 | nM | 6.46 | Inhibition In Vito Assay: The investigations on the inhibition of the recombinan... | - |
Data from ChEMBL 36 via Core Engine