Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL575987

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CCCNC1CCN(S(=O)(=O)CCC2CCc3ccccc3N2S(=O)(=O)c2ccc(OC)cc2OC)CC1

Basic Information

ChEMBL ID CHEMBL575987
Phase Preclinical
Structure Type MOL
InChI Key XPPJMZLNLXTIMY-UHFFFAOYSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

565.8
MW (Da)
3.40
ALogP
7
HBA
1
HBD
105.2
PSA (Ų)
0.45
QED
1
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H39N3O6S2
MW 565.76
Aromatic Rings 2
Heavy Atoms 38
NP-Likeness -1.05

Activity Summary

Ki 3 meas. best 6.82

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Vasopressin V1b receptor
CHEMBL1921
Ki 6.82 6.82 152.0 1
Vasopressin V1b receptor
CHEMBL2659
Ki 6.64 6.64 227.0 1
Vasopressin V1a receptor
CHEMBL1889
Ki 5.9 5.9 1268.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
19800231 10.1016/j.bmcl.2009.09.050 Vasopressin V1b receptor 2
19800231 10.1016/j.bmcl.2009.09.050 Vasopressin V1a receptor 1

Data from ChEMBL 36 via Core Engine