Compound Detail
CHEMBL5772598
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Basic Information
| ChEMBL ID | CHEMBL5772598 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FOKDTUHZKJGPII-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
440.5
MW (Da)
4.65
ALogP
6
HBA
3
HBD
110.2
PSA (Ų)
0.54
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 8.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL260 | IC50 | 8.22 | 8.22 | 6.0 | 2 |
| Mitogen-activated protein kinase 13 CHEMBL2939 | IC50 | 8.22 | 8.22 | 6.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | IC50 | = | 6.0 | nM | 8.22 | MAPK13 and MAPK14 enzyme assays: ach of these analogs were checked for physical ... | - |
| Mitogen-activated protein kinase 13 | IC50 | = | 6.0 | nM | 8.22 | MAPK13 and MAPK14 enzyme assays: ach of these analogs were checked for physical ... | - |
| Mitogen-activated protein kinase 14 | IC50 | = | 6.0 | nM | 8.22 | MAPK13 and MAPK14 enzyme assays: ach of these analogs were checked for physical ... | - |
Data from ChEMBL 36 via Core Engine