Compound Detail
CHEMBL5846428
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Basic Information
| ChEMBL ID | CHEMBL5846428 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VDMAEHSLZZVIGO-UWVGGRQHSA-N |
5
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
242.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 5.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 5.28 | 5.28 | 5200.0 | 1 |
| Dipeptidyl peptidase 2 CHEMBL3976 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
| Dipeptidyl peptidase 9 CHEMBL4793 | IC50 | 4.8 | 4.8 | 16000.0 | 1 |
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 4.68 | 4.68 | 21000.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.55 | 4.55 | 28000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 8 | IC50 | = | 5200.0 | nM | 5.28 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 2 | IC50 | = | 10000.0 | nM | 5.0 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 9 | IC50 | = | 16000.0 | nM | 4.8 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 4 | IC50 | = | 21000.0 | nM | 4.68 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Unchecked | IC50 | = | 28000.0 | nM | 4.55 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
Data from ChEMBL 36 via Core Engine