Compound Detail
CHEMBL5891981
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Basic Information
| ChEMBL ID | CHEMBL5891981 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XYJWIHFCSQUHLU-AWEZNQCLSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
312.4
MW (Da)
2.72
ALogP
5
HBA
0
HBD
60.2
PSA (Ų)
0.82
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 CHEMBL6159 | IC50 | 6.26 | 6.26 | 550.0 | 2 |
| Ubiquitin carboxyl-terminal hydrolase 30 CHEMBL4523357 | IC50 | 5.26 | 5.26 | 5500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 | IC50 | = | 550.0 | nM | 6.26 | UCHL1 Biochemical IC50 Assay: Dilution plates were prepared at 21 times the fina... | - |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 | IC50 | = | 550.0 | nM | 6.26 | USP30 Biochemical IC50 Assay: Dilution plates were prepared at 21 times the fina... | - |
| Ubiquitin carboxyl-terminal hydrolase 30 | IC50 | = | 5500.0 | nM | 5.26 | USP30 Biochemical IC50 Assay: Dilution plates were prepared at 21 times the fina... | - |
| Ubiquitin carboxyl-terminal hydrolase 30 | IC50 | = | 5500.0 | nM | 5.26 | UCHL1 Biochemical IC50 Assay: Dilution plates were prepared at 21 times the fina... | - |
Data from ChEMBL 36 via Core Engine