Compound Detail
CHEMBL5893181
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Basic Information
| ChEMBL ID | CHEMBL5893181 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KXQSVQUUJQXHIX-HNNXBMFYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
439.9
MW (Da)
4.12
ALogP
8
HBA
0
HBD
93.2
PSA (Ų)
0.57
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.32
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bromodomain-containing protein 4 CHEMBL1163125 | IC50 | 7.32 | 7.32 | 48.0 | 1 |
| Bromodomain testis-specific protein CHEMBL1795185 | IC50 | 6.88 | 6.88 | 132.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bromodomain-containing protein 4 | IC50 | = | 48.0 | nM | 7.32 | ATPLITE assay: Acetyl-Histone Binding Assay. Assays were performed as described ... | - |
| Bromodomain testis-specific protein | IC50 | = | 132.0 | nM | 6.88 | ATPLITE assay: Acetyl-Histone Binding Assay. Assays were performed as described ... | - |
Data from ChEMBL 36 via Core Engine