Compound Detail
CHEMBL59436
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Basic Information
| ChEMBL ID | CHEMBL59436 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AGZGVZURSIWOCV-CMDGGOBGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
407.4
MW (Da)
5.28
ALogP
3
HBA
1
HBD
55.4
PSA (Ų)
0.59
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Capsid scaffolding protein CHEMBL3771 | IC50 | 8.18 | 8.18 | 6.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Capsid scaffolding protein | IC50 | = | 6.6 | nM | 8.18 | Inhibitory concentration against HCMV protease. | 15055990 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15055990 | 10.1021/jm030540h | Capsid scaffolding protein | 1 |
| 15055990 | 10.1021/jm030540h | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine