Compound Detail
CHEMBL595439
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL595439 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QRXBDPYWCAAAAI-UXDJRKLDSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
248.2
MW (Da)
-4.00
ALogP
7
HBA
6
HBD
148.3
PSA (Ų)
0.26
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 4.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form CHEMBL4696 | Ki | 4.54 | 4.54 | 28600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form | Ki | = | 28600.0 | nM | 4.54 | Inhibition of rabbit muscle glycogen phosphorylase b | 19781947 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19781947 | 10.1016/j.bmc.2009.08.060 | Glycogen phosphorylase, muscle form | 1 |
| 22325154 | 10.1016/j.bmc.2011.12.059 | Glycogen phosphorylase, muscle form | 1 |
| 26708111 | 10.1016/j.ejmech.2015.12.004 | Glycogen phosphorylase, muscle form | 1 |
| 31251604 | 10.1021/acs.jmedchem.9b00356 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine