Compound Detail
CHEMBL596507
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL596507 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DTOUHNVAVIMSRE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
373.4
MW (Da)
4.55
ALogP
3
HBA
1
HBD
59.3
PSA (Ų)
0.57
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL216 | EC50 | 7.08 | 7.08 | 84.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | EC50 | = | 84.0 | nM | 7.08 | Positive allosteric modulation activity at muscarinic M1 receptor | 22148748 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20004574 | 10.1016/j.bmcl.2009.11.100 | Serum | 2 |
| 20004574 | 10.1016/j.bmcl.2009.11.100 | Muscarinic acetylcholine receptor M1 | 1 |
| 22148748 | 10.1021/jm201139r | Muscarinic acetylcholine receptor M1 | 1 |
Data from ChEMBL 36 via Core Engine