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Compound Detail

CHEMBL6008883

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Cc1csc(Nc2nnc(N)nc2-c2ccccc2)n1

Basic Information

ChEMBL ID CHEMBL6008883
Phase Preclinical
Structure Type MOL
InChI Key HKUXCZJOGNAUSQ-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

284.4
MW (Da)
2.63
ALogP
7
HBA
2
HBD
89.6
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C13H12N6S
MW 284.35
Aromatic Rings 3
Heavy Atoms 20
NP-Likeness -1.72

Activity Summary

Ki 2 meas. best 6.71

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Adenosine receptor A1
CHEMBL226
Ki 6.71 6.71 195.0 1
Adenosine receptor A2a
CHEMBL251
Ki 5.07 5.07 8511.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine