Compound Detail
CHEMBL6027642
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6027642 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FHRDWVDQXHXEPT-UHFFFAOYSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
423.4
MW (Da)
3.17
ALogP
6
HBA
2
HBD
87.0
PSA (Ų)
0.64
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 10.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| cGMP-dependent 3',5'-cyclic phosphodiesterase CHEMBL2652 | Ki | 10.62 | 10.0 | 0.0 | 2 |
| Unchecked CHEMBL612545 | Ki | 10.44 | 9.9 | 0.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Ki | = | 0.024 | nM | 10.62 | Lab B PDE2 assay: Performed by Lab B. The activity of the compounds in accordanc... | - |
| Unchecked | Ki | = | 0.036 | nM | 10.44 | Lab B PDE2 assay: Performed by Lab B. The activity of the compounds in accordanc... | - |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Ki | = | 0.42 | nM | 9.38 | Lab B PDE2 assay: Performed by Lab B. The activity of the compounds in accordanc... | - |
| Unchecked | Ki | = | 0.44 | nM | 9.36 | Lab B PDE2 assay: Performed by Lab B. The activity of the compounds in accordanc... | - |
Data from ChEMBL 36 via Core Engine