Compound Detail
CHEMBL61735
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Basic Information
| ChEMBL ID | CHEMBL61735 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XLXYTDQVAZQQMX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
398.3
MW (Da)
3.88
ALogP
4
HBA
3
HBD
88.0
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL260 | IC50 | 6.6 | 6.6 | 250.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | IC50 | = | 250.0 | nM | 6.6 | Inhibition of mitogen-activated protein kinase p38 alpha 2 | 10999468 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10999468 | 10.1016/s0960-894x(00)00272-9 | Mitogen-activated protein kinase 14 | 2 |
Data from ChEMBL 36 via Core Engine