Compound Detail
CHEMBL63960
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL63960 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QEKNVGHVGOCWDS-AATRIKPKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
300.4
MW (Da)
3.89
ALogP
4
HBA
0
HBD
36.9
PSA (Ų)
0.76
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 5.24 | 5.24 | 5800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 5800.0 | nM | 5.24 | Inhibitory effect on PGE-2 production in LPS-stimulated RAW264.7 cells | 15080988 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15080988 | 10.1016/j.bmcl.2004.02.038 | RAW264.7 | 1 |
Data from ChEMBL 36 via Core Engine