Compound Detail
CHEMBL6410
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Basic Information
| ChEMBL ID | CHEMBL6410 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BFXFDLMTMKFDSG-YHZPTAEISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
607.6
MW (Da)
9.48
ALogP
2
HBA
0
HBD
12.5
PSA (Ų)
0.10
QED
2
Ro5 Violations
14
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Phosphodiesterase 1 CHEMBL2095150 | IC50 | 6.7 | 6.7 | 200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Phosphodiesterase 1 | IC50 | = | 200.0 | nM | 6.7 | Inhibitory activity against calmodulin-dependent Phosphodiesterase was reported. | 8632423 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8632423 | 10.1021/jm9505472 | Phosphodiesterase 1 | 2 |
| 8632423 | 10.1021/jm9505472 | Estrogen receptor | 1 |
Data from ChEMBL 36 via Core Engine