Compound Detail
CHEMBL65406
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Basic Information
| ChEMBL ID | CHEMBL65406 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKCMADOPPWWGNZ-HTQZYQBOSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
214.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 5.4 | 5.4 | 4000.0 | 1 |
| Dipeptidyl peptidase 2 CHEMBL3976 | IC50 | 4.75 | 4.75 | 18000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | IC50 | = | 4000.0 | nM | 5.4 | In vitro for inhibition of Dipeptidylpeptidase IV. | 8642568 |
| Dipeptidyl peptidase 2 | IC50 | = | 18000.0 | nM | 4.75 | Compound was tested in vitro for inhibition of Dipeptidylpeptidase II | 8642568 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8642568 | 10.1021/jm950732f | Dipeptidyl peptidase 4 | 1 |
| 8642568 | 10.1021/jm950732f | Dipeptidyl peptidase 2 | 1 |
| 8642568 | 10.1021/jm950732f | Prolyl endopeptidase | 1 |
Data from ChEMBL 36 via Core Engine