Compound Detail
CHEMBL665
N-METHYL PYRROLIDINE (NMP) Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL665 |
| Name | N-METHYL PYRROLIDINE (NMP) |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AVFZOVWCLRSYKC-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
85.2
MW (Da)
0.71
ALogP
1
HBA
0
HBD
3.2
PSA (Ų)
0.42
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 4.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuronal acetylcholine receptor CHEMBL2094110 | Kd | 4.28 | 4.28 | 52000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor | Kd | = | 52000.0 | nM | 4.28 | Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fractio... | 4032427 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 4032427 | 10.1021/jm00147a021 | Neuronal acetylcholine receptor | 6 |
| 22542016 | 10.1016/j.bmcl.2012.04.009 | No relevant target | 1 |
| 22542016 | 10.1016/j.bmcl.2012.04.009 | Unchecked | 1 |
| 24249037 | 10.1007/s11095-013-1232-z | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine