Compound Detail
CHEMBL68073
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Basic Information
| ChEMBL ID | CHEMBL68073 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CZDYPVPMEAXLPK-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
88.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 integrase CHEMBL3471 | IC50 | 5.3 | 5.035 | 5000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 integrase | IC50 | = | 5000.0 | nM | 5.3 | Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transfer | 10841789 |
| Human immunodeficiency virus type 1 integrase | IC50 | = | 17000.0 | nM | 4.77 | Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessing | 10841789 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10841789 | 10.1021/jm990322h | Human immunodeficiency virus type 1 integrase | 2 |
Data from ChEMBL 36 via Core Engine