Compound Detail
CHEMBL71589
PILOCARBINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL71589 |
| Name | PILOCARBINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DIGNPNFFGGTFOC-YUMQZZPRSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
194.2
MW (Da)
1.09
ALogP
4
HBA
0
HBD
44.1
PSA (Ų)
0.66
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor CHEMBL1907609 | Ki | 7.08 | 6.54 | 82.9 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor | Ki | = | 82.91 | nM | 7.08 | Inhibition of [3H]- Oxo-M binding to muscarinic acetylcholine receptor of rat br... | 1613746 |
| Muscarinic acetylcholine receptor | Ki | = | 1011.0 | nM | 6.0 | Inhibition of [3H]QNB binding to muscarinic acetylcholine receptor of rat heart ... | 1613746 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1613746 | 10.1021/jm00090a006 | Muscarinic acetylcholine receptor | 2 |
Data from ChEMBL 36 via Core Engine