Compound Detail
CHEMBL71927
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Basic Information
| ChEMBL ID | CHEMBL71927 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YCFJZPGDTZVVSM-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
298.3
MW (Da)
2.74
ALogP
5
HBA
0
HBD
79.6
PSA (Ų)
0.63
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase CHEMBL247 | IC50 | 6.4 | 6.4 | 400.0 | 1 |
| Human immunodeficiency virus 1 CHEMBL378 | IC50 | 6.4 | 6.4 | 400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase | IC50 | = | 400.0 | nM | 6.4 | In vitro inhibitory activity against human immunodeficiency virus type 1 (HIV-1)... | 1712395 |
| Human immunodeficiency virus 1 | IC50 | = | 400.0 | nM | 6.4 | Concentration required to inhibit 50% viral production of human immunodeficiency... | 15801834 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1712395 | 10.1021/jm00111a045 | Human immunodeficiency virus type 1 reverse transcriptase | 2 |
| 15801834 | 10.1021/jm049606e | Human immunodeficiency virus 1 | 1 |
Data from ChEMBL 36 via Core Engine